Epinephrine is an injection-based medication used to treat life-threatening allergic reactions called anaphylaxis* (an-a-fi-LAK-sis). These very serious reactions are most commonly caused by foods, drugs and stinging insects. People with severe allergy or a history of anaphylaxis should carry (2) auto injectable epinephrine with them at all times. Epinephrine typically comes as a single-dose pre-filled automatic injection device to be injected into the thigh. In some very severe cases, patients may require a second dose of epinephrine after a few minutes to stop the anaphylactic shock and avoid death. After you use the automatic injection device, go the closest emergency room immediately. Later, check back with your allergist.