Penicillin are the most prescribed group of antibiotics, and delayed rashes are frequently reported in children.
About 80% people will lose their penicillin allergy if they avoid the drug for 10 years. However, a patient with the “penicillin allergic label” consequently the optimal antibiotic treatment would be denied and more likely will be prescribed a less effective alternative, more expensive and usually associated with more side effects.
Therefore penicillin allergy testing should be performed routinely in patients with self-reported penicillin allergy. The evaluation performed by an allergist/ immunologist specialist requires an initial skin testing, followed by an oral challenge.